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Cleavage products formed through autoxidation of ζ-carotene were evaluated to elucidate possible oxidation products of ζ-carotene under oxidative condition. ζ-Carotene, solubilized at 50μM in liposomal suspension, was oxidized by incubating at 37℃ for 72 hr. Among oxidation products formed, five products in carbonyl compound fraction were identified as 6,10,14-trimethylpentadeca-3,5,9,13-tetraen-2-one, 3,7,11,15-tetramethylhexadeca-2,4,6,10,14-pentaenal (phytapentaenal), 5,9,13,17-tetramethyloctadeca-2,4,6,8,10,12,16,20-octaenal, which correspond to products formed through caleavage in five conjugated double bonds of ζ-carotene. 4,5-Didehydrogeranyl geranoic acid was also formed through autoxidation of ζ-carotene in loposomal suspension. These results suggest that ζ-carotene is cleaved into long- and short-chain carbonyl compounds under oxidative condition.
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